Skip to main content
Figure 4 | Arthritis Research & Therapy

Figure 4

From: Mechanisms of B cell autoimmunity in SLE

Figure 4

Characteristics of somatic hypermutation and generation of autoantibodies. AID, activation-induced cytidine deaminase; CDR, complementarity-determining region; Ig, immuonglobulin; RGYW, purine (R), guanine (G), pyrimidine (Y), adenine/thymine (W); S → R, silent-to-replacement; SHM, somatic hypermutation; WRCY, adenine/thymine (W), purine (R), cytosine (C), pyrimidine (Y).

Back to article page

Arthritis Research & Therapy

ISSN: 1478-6362

Contact us