CCR5Δ32 variant and cardiovascular disease in patients with rheumatoid arthritis: a cohort study

Table 3 Cox regression model to estimate the influence of the CCR5Δ32 polymorphism in the risk of cardiovascular disease in patients with rheumatoid arthritis^a

Patient group characteristics	P value	HR (95% CI)	P value^b	HR (95% CI)^b
Carriers vs. noncarriers^c	0.14	0.42 (0.13 to 1.33)	0.14	0.42 (0.13 to 1.33)
Carriers vs. noncarriers^d	0.078	0.35 (0.11 to 1.12)	0.097	0.37 (0.12 to 1.19)

^aHR (95% CI): hazard ratio with 95% confidence interval. ^bAnalyses adjusted for gender, age at rheumatoid arthritis (RA) diagnosis, presence or absence of shared epitope, rheumatoid factor, hypertension, diabetes, dyslipidemia, obesity and smoking habit. ^cUsing as survival time the patient's age at the time of the first cardiovascular event, patient's death, loss of follow-up or 1 December 2009. ^dUsing as survival time the elapsed time between RA diagnosis and the time of the first cardiovascular event, the patient's death, loss of follow-up or 1 December 2009.