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Table 4 Comparison of carotid artery intima-media thickness, flow-mediated endothelium-dependent (postischemia) vasodilatation and endothelium-independent vasodilatation according to the CCR5Δ32 polymorphism distributiona

From: CCR5Δ32 variant and cardiovascular disease in patients with rheumatoid arthritis: a cohort study

CCR5Δ32polymorphism Mean IMT, mm (SD) P value Mean FMD % (SD) P value Mean NTG % (SD) P value
CCR5/CCR5 (n = 95) 0.73 (0.16)      
CCR5/CCR5Δ32 (n = 10) 0.79 (0.32)      
CCR5Δ32/CCR5Δ32 (n = 0) - 0.32     
CCR5/CCR5 (n = 113)    5.51 (4.66)   17.2 (7.64)  
CCR5/CCR5Δ32 (n = 14)    7.03 (6.61)   18.21 (8.45)  
CCR5Δ32/CCR5Δ32 (n = 0)    - 0.28 - 0.64
  1. aIMT: intima-media thickness; FMD: flow-mediated endothelium-dependent (postischemia) vasodilatation; NTG: endothelium-independent (postnitroglycerin) vasodilatation.