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Table 5 Comparison of carotid artery intima-media thickness, flow-mediated endothelium-dependent (postischemia) vasodilatation and endothelium-independent vasodilatation according to a recessive pattern of effect of CCR5Δ32 polymorphism in an analysis of covariance modela

From: CCR5Δ32 variant and cardiovascular disease in patients with rheumatoid arthritis: a cohort study

 

P value

CCR5Δ32group

IMT

FMD

NTG

Carriers vs. noncarriers

0.77

0.024

0.11

  1. aFMD: flow-mediated endothelium-dependent vasodilatation; IMT: carotid artery intima-media thickness; NTG: endothelium-independent (postnitroglycerin) vasodilatation. Analyses were adjusted for gender, age at the time of ultrasonography, follow-up time, and presence or absence of rheumatoid shared epitope, hypertension, diabetes, dyslipidemia, obesity and smoking habit.