Example of non-sensitivity of radiography. (a) Baseline coronal intermediate-weighted magnetic resonance imaging shows hyperintensity in the weight-bearing portion of the lateral tibial plateau but no definite cartilage defect. (b) At 24-month follow-up, an incident focal full-thickness defect has developed in the corresponding area of the lateral tibial plateau (arrows). (c) Baseline anteroposterior radiograph does not show any joint space narrowing in the lateral tibiofemoral joint. (d) No change to baseline is observed at 24-month follow-up.