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Table 3 Coincidence* of autoantibodies in 863 individual systemic sclerosis patients

From: Frequency of disease-associated and other nuclear autoantibodies in patients of the German network for systemic scleroderma: correlation with characteristic clinical features

Antibodies ACA ATA Anti-PM-Scl Anti-U1-RNP Anti-RNAP Anti-fibrilla-rin Anti-To Anti-Ku Anti-Jo-1/Pl-7/OJ Anti-U11-RNP Anti-Ro52 Anti-Ro60 Anti-La AMA Anti-p25/p23 Anti-NOR-90 Anti-SL Anti-Sm Anti-Sp100 Other
ACA   1 0 1 0 0 0 0 0 0 92 11 1 31 28 4 2 0 3 144
ATA    1 2 0 0 0 4 0 0 36 26 6 4 0 1 4 1 0 77
Anti-PM-Scl     0 0 0 0 1 0 0 6 2 0 0 0 0 0 0 0 4
Anti-U1-RNP      1 0 0 0 0 0 11 6 1 2 0 1 0 4 0 11
Anti-RNAP       0 0 0 0 0 5 1 1 1 0 0 1 0 0 5
Anti-fibrillarin        0 0 0 0 0 0 0 1 0 0 0 0 0 8
Anti-To         0 0 0 1 1 0 0 0 0 0 0 0 2
Anti-Ku          0 0 2 2 0 0 0 0 1 0 0 2
Anti-Jo-1/Pl-7/OJ           0 3 0 0 0 0 0 0 0 0 1
Anti-U11-RNP            0 0 0 0 0 0 0 0 0 0
Anti-Ro52             41 15 14 11 2 5 2 2 97
Anti-Ro60              14 6 0 0 0 1 1 33
Anti-La               1 0 0 0 1 0 8
AMA                2 0 1 1 2 29
Anti-p25/p23                 1 1 0 1 18
Anti-NOR-90                  0 1 0 4
Anti-SL                   0 0 3
Anti-Sm                    0 0
Anti-Sp100                     2
Other                     
Isolateda 104 153 31 19 23 4 0 4 1 1 2 1 0 0 0 0 1 0 0 79
Totalb 310 260 42 41 33 12 2 10 4 1 187 59 16 41 28 6 9 4 4 363
  1. *Number of patients with co-occurrences of autoantibodies. aIsolated: presence without coincidence of any other autoantibody by all detection methods used. bTotal number of individuals with the respective autoantibody; these numbers mostly are smaller than the sum of all co-occurrences plus the 'isolated' individuals listed because of some triple, quadruple and higher-order coincidences. ACA = anti-centromere antibodies; AMA = antimitochondrial antibodies; ATA = anti-topoisomerase I antibodies;; RNAP = RNA polymerase; RNP = ribonucleoprotein.