| SLE patients | Healthy controls | P-value |
---|
sRANKL | 0.40 (0.02 to 25.99) | 0.40 (0.29 to 67.64) | 0.372 |
OPG | 69.02 (17.42 to 500.90) | 95.14 (1.56 to 1069.13) | < 0.001 |
sRANKL/OPG ratio | 0.0103 (0.001 to 0.817) | 0.0056 (0.000 to 1.866) | 0.010 |
- Values represent median (IQR). Differences were assessed by non-parametric Mann-Whitney U test.
- In 49.5% of SLE patients and 63.2% of healthy controls, the sRANKL levels were below the limit of detection (LOD) of the quantification method. Regarding OPG quantification, there were no samples with concentrations below the LOD.
- IQR, interquartile range; OPG, osteoprotegerin; SLE, Systemic Lupus Erythematosus; sRANKL, soluble RANKL