| |
SLE patients
|
Healthy controls
|
P-value
|
|---|
|
sRANKL
|
0.40 (0.02 to 25.99)
|
0.40 (0.29 to 67.64)
|
0.372
|
|
OPG
|
69.02 (17.42 to 500.90)
|
95.14 (1.56 to 1069.13)
|
< 0.001
|
|
sRANKL/OPG ratio
|
0.0103 (0.001 to 0.817)
|
0.0056 (0.000 to 1.866)
|
0.010
|
- Values represent median (IQR). Differences were assessed by non-parametric Mann-Whitney U test.
- In 49.5% of SLE patients and 63.2% of healthy controls, the sRANKL levels were below the limit of detection (LOD) of the quantification method. Regarding OPG quantification, there were no samples with concentrations below the LOD.
- IQR, interquartile range; OPG, osteoprotegerin; SLE, Systemic Lupus Erythematosus; sRANKL, soluble RANKL
