|
Gene and SNP
|
Position
a
|
Minor allele
|
Minor allele frequency
|
P value
|
Corrected P value
b
|
Odds ratio (95% confidence interval)
|
|---|
| | | |
Case
|
Control
| | | |
|---|
|
FCGR3A
| | | | | | | |
|
rs11581823
|
1:161517384
|
C
|
0.0830
|
0.0975
|
0.28
| |
0.84 (0.62 to 1.14)
|
|
rs7539036
|
1:161512731
|
T
|
0.0580
|
0.0714
|
0.25
| |
0.80 (0.56 to 1.14)
|
|
FCGR2A
| | | | | | | |
|
rs4656308
|
1:161478751
|
C
|
0.1602
|
0.1456
|
0.36
| |
1.12 (0.88 to 1.42)
|
|
rs1801274
|
1:161479745
|
G
|
0.3565
|
0.34
|
0.43
| |
1.08 (0.90 to 1.29)
|
|
TNFAIP3
| | | | | | | |
|
rs5029924
|
6:138187498
|
T
|
0.0817
|
0.0470
|
0.0017
|
0.030
|
1.80 (1.25 to 2.61)
|
|
rs5029937
|
6:138195151
|
T
|
0.0812
|
0.0448
|
0.0006
|
0.012
|
1.88 (1.30 to 2.73)
|
|
rs2230926
|
6:138196066
|
G
|
0.0811
|
0.0448
|
0.0007
|
0.012
|
1.88 (1.30 to 2.72)
|
|
rs610604
|
6:138199417
|
G
|
0.0989
|
0.0984
|
1.00
| |
1.00 (0.75 to 1.34)
|
|
TLR9
| | | | | | | |
|
rs187084
|
3:52261031
|
C
|
0.3773
|
0.3722
|
0.82
| |
1.02 (0.85 to 1.22)
|
|
rs352140
|
3:52256697
|
A
|
0.3686
|
0.3635
|
0.82
| |
1.02 (0.86 to 1.22)
|
|
rs352162
|
3:52252969
|
G
|
0.3850
|
0.3770
|
0.72
| |
1.04 (0.87 to 1.24)
|
|
TREX1
| | | | | | | |
|
rs2242150
|
3:48505964
|
A
|
0.3535
|
0.3340
|
0.35
| |
1.09(0.91 to 1.31)
|
|
rs3135941
|
3:48507667
|
C
|
0.0326
|
0.0392
|
0.47
| |
0.82 (0.52 to 1.32)
|
|
ETS1
| | | | | | | |
|
rs6590330
|
11:128311059
|
A
|
0.4258
|
0.3086
|
3.0 × 10-8
|
5.5 × 10
-7
|
1.66 (1.39 to 1.99)
|
|
rs4937333
|
11:128330520
|
T
|
0.4814
|
0.3652
|
9.3 × 10
-8
|
1.7 × 10
-6
|
1.61 (1.35 to 1.92)
|
|
TNIP1
| | | | | | | |
|
rs13168551
|
5:150462638
|
T
|
0.2211
|
0.2505
|
0.14
| |
0.85 (0.69 to 1.05)
|
|
rs7708392
|
5:150457485
|
G
|
0.2132
|
0.2587
|
0.02
|
0.39
|
0.78 (0.63 to 0.96)
|
|
rs10036748
|
5:150458146
|
C
|
0.2196
|
0.2552
|
0.08
| |
0.82 (0.66 to 1.02)
|
- Bold data are significant. aGenomic positions from NCBI Genome Build 37.1 (GRCh37) [56]. bP values calculated by Fisher's exact test and then corrected by the Bonferroni criterion.
