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Table 4 Differential protein spots in pSS, RA-sSS and SSc-sSS (P <0

From: Proteomic analysis of saliva: a unique tool to distinguish primary Sjögren's syndrome from secondary Sjögren's syndrome and other sicca syndromes

Spot No Accession No Protein name Gene name Mean ± SD
(pSS)
Mean ± SD
(RA- sSS)
Mean ± SD
(SSc-sSS)
Fold of variation
pSS vsRA- sSS
Fold of variation
pSS vsSSc-sSS
3017 P06702 (Protein S100-A9)
Calgranulin B
S100A9 0.15 ± 0.07 0.37 ± 0.07 - -2.46* -
3034 P06702 (Protein S100-A9)
Calgranulin B
S100A9 0.20 ± 0.09 0.56 ± 0.17 - -2.8* -
2439 P06733 α-enolase ENO1 0.13 ± 0.02 0.05 ± 0.02 - +2.6** -
2543 P06733 α-enolase ENO1 0.08 ± 0.02 0.19 ± 0.03 - -2.4** -
2842 Q6GMW1 IGKC IGKC 1.33 ± 0.49 0.05 ± 0.09 - +26* -
2832 A0N5G5 Rheumatoid factor D5
light chain
V<KAPPA>3 1.97 ± 0.11 0.29 ± 0.26 - +6.8*** -
2954 P31025 Lipocalin LCN1 0.06 ± 0.05 0.37 ± 0.07 - -6.2** -
3036 P61769 β-2 microglobulin B2M 0.39 ± 0.04 0.25 ± 0.04 0.25 ± 0.03 +1.6* +1.6*
2642 P04406 G3PDH G3PDH 0.07 ± 0.03 - 0.19 ± 0.10 - -2.7*
2996 P01034 Cystatin-C CST3 0.21 ± 0.08 - 0.05 ± 0.04 - -4.2*
  1. NB, values that are significantly different from pSS (*P <0.05, **P <0.01, ***P <0.001) as determined by statistical analysis.
  2. G3PDH, glyceraldehydes-3-phosphate dehydrogenase; IGKC, immunoglobulin k light chain; pSS, primary Sjögren's syndrome; RA-sSS, secondary Sjögren's syndrome concomitant to rheumatoid arthritis; SSc-sSS, secondary Sjögren's syndrome concomitant to systemic sclerosis