Table 1 Summary of studies demonstrating a type I interferon signature in dermatomyositis muscle or blood
From: Type I interferon pathway in adult and juvenile dermatomyositis
Reference | Array format (approximate number of genes) or other platform | Tissue | Sample size |
|---|---|---|---|
Tezak and colleagues [4] | Affymetrix HuFL (5,600) | Muscle | 4 JDM |
Zhou and colleagues [6] | cDNA (4,000) | Muscle | 6 PM, 4 DM |
Greenberg and colleagues [7] | Affymetrix U133A (16,000) | Muscle | 13 DM, 6 PM, 20 IBM |
Raju and Dalakas [9] | Affymetrix U133A (16,000) | Muscle | 3 DM, 4 IBM |
Chen and colleagues [5] | Affymetrix U133A (16,000) | Muscle | 31 JDM |
Salajegheh and colleagues [8] | Affymetrix U133A (16,000) | Muscle | 14 DM, 24 IBM, 38 PM/other |
O'Connor and colleagues [16] | Quantitative real-time RT-PCR | Blood | 14 JDM |
Walsh and colleagues [24] | Affymetrix U133A 2.0+ (38,500) | Blood | 12 DM, 11 PM, 13 IBM |
Baechler and colleagues [23] | Affymetrix U133A 2.0+ (38,500) | Blood | 10 DM, 2 JDM |
Bilgic and colleagues [25] | Quantitative real-time RT-PCR | Blood | 37 DM, 19 JDM |
Liao and colleagues [26] | Affymetrix U133A 2.0+ (38,500) | Blood | 24 DM, 12 PM, 15 IBM, 7 othera |