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Table 1 Top 25 differentially up- and down-regulated genes by log fold change (LogFC)

From: Tight regulation of wingless-type signaling in the articular cartilage - subchondral bone biomechanical unit: transcriptomics in Frzb-knockout mice

Up-regulated genes Down-regulated genes
Symbol Name LogFC Symbol Name LogFC
Dbp D site albumin promoter binding protein 3.551 Olfm4 olfactomedin 4 -4.248
Pck1 phosphoenolpyruvate carboxykinase 1, cytosolic 2.836 Igkv15-103 immunoglobulin kappa chain variable 15-103 -4.238
Rbm45 RNA binding motif protein 45 2.689 Apol11b apolipoprotein L 11b -4.151
Aspn asporin 2.464 Frzb frizzled-related protein -3.606
Angptl7 angiopoietin-like 7 2.461 Mmp8 matrix metallopeptidase 8 -3.531
Htra4 HtrA serine peptidase 4 2.442 Cd5l CD5 antigen-like -3.442
Nnat neuronatin 2.367 Slfn1 schlafen 1 -3.388
Epha3 Eph receptor A3 2.367 Apol8 apolipoprotein L 8 -3.345
Lrrn4cl LRRN4 C-terminal like 2.355 Car1 carbonic anhydrase 1 -3.338
Angptl1 angiopoietin-like 1 2.344 Gypa glycophorin A -3.328
Matn4 matrilin 4 2.315 Spna1 spectrin alpha 1 -3.294
Olfml1 olfactomedin-like 1 2.276 Myb myeloblastosis oncogene -3.264
Col14a1 collagen, type XIV, alpha 1 2.260 Epb4.2 erythrocyte protein band 4.2 -3.245
Cdh13 cadherin 13 2.230 Ceacam10 carcinoembryonic antigen-related cell adhesion molecule 10 -3.218
Col14a1 collagen, type XIV, alpha 1 2.202 Spna1 spectrin alpha 1 -3.175
Sfrp1 secreted frizzled-related protein 1 2.199 Cd177 CD177 antigen -3.173
Pck1 phosphoenolpyruvate carboxykinase 1, cytosolic 2.189 Igj immunoglobulin joining chain -3.158
Dkk3 dickkopf homolog 3 (Xenopus laevis) 2.166 Gypa glycophorin A -3.156
Nr1d2 nuclear receptor subfamily 1, group D, member 2 2.142 Rhd Rh blood group, D antigen -3.152
Adrb3 adrenergic receptor, beta 3 2.138 Fam55b family with sequence similarity 55, member B -3.151
Gnas guanine nucleotide binding protein, alpha stimulating 2.132 Abca13 ATP-binding cassette, sub-family A (ABC1), member 13 -3.142
Dkk2 dickkopf homolog 2 (Xenopus laevis) 2.131 Mylk3 myosin light chain kinase 3 -3.139
Hmcn1 hemicentin 1 2.116 Ankrd43 ankyrin repeat domain 43 -3.135
Gpr1 G protein-coupled receptor 1 2.115 Ifitm6 interferon induced transmembrane protein 6 -3.128
Lrrc15 leucine rich repeat containing 15 2.110 Myb myeloblastosis oncogene -3.111