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Table 1 Main baseline features of the 13 patients meeting ASAS criteria [30] for axial spondyloarthritis

From: Is IL-6 an appropriate target to treat spondyloarthritis patients refractory to anti-TNF therapy? a multicentre retrospective observational study

  Patient 1 Patient 2 Patient 3 Patient 4 Patient 5 Patient 6 Patient 7
Type of SpA AS AS AS AS AS AS AS
Sacroiliitis Grade 4 Grade 4 Grade 3 Grade 4 Grade 3 Grade 3 Grade 4
HLA-B27 + + + + + + +
Gender Female Female Female Male Male Female Male
Disease duration (years) 9 27 11 6 4 24 19
Main location of inflammatory pain Back, neck, chest, peripheral enthesitis (Achilles tendon, knee) Neck, chest, peripheral enthesitisa Back, buttock, chest Neck Back, neck, buttock Back, neck, chest Back, neck, peripheral enthesitis (Achilles tendon)
Concomitant NSAIDs/steroids (dosage) Yes/no Yes/no Yes/no No/no No/no Yes/no Yes/no
Concomitant DMARDs No No No Sulfasalazine No No No
Previous biologics other than anti-TNF Abatacept Abatacept Abatacept No No No No
  Patient 8 Patient 9 Patient 10 Patient 11 Patient 12 Patient 13  
Type of SpA AS and PsA uSpA uSpA uSpA uSpA uSpA  
Sacroiliitis Grade 3 Grade 1 Grade 0 Grade 0 Grade 0 Grade 0  
HLA-B27 - + + + + +  
Gender Male Female Female Male Female Male  
Disease duration (years) 15 11 9 25 6 12  
Main location of inflammatory pain Back, neck, arthritis Back, neck, buttock, chest Back, buttock Back, neck, buttock Back, buttock, chest, peripheral enthesitis (Achilles tendon) Back, neck  
Concomitant NSAIDs/steroids (dosage) No/no Yes/no Yes/no No/no Yes/no No/yes (25 mg/day)  
Concomitant DMARDs No No No No No No  
Previous biologics other than anti-TNF Rituximab Abatacept Abatacept No No No  
  1. AS, ankylosing spondylitis meeting modified New York criteria [33]; ASAS, Assessment of SpondyloArthritis International Society; DMARD, disease-modifying antirheumatic drug; NSAID, nonsteroidal anti-inflammatory drug; PsA, psoriatic arthritis meeting Classification Criteria for Psoriatic Arthritis [36]; SpA, spondyloarthritis; uSpA, undifferentiated spondyloarthritis. aLocation unknown.