Figure 3

Decreased frequency of naïve T cells (T _N ) and unreduced frequency of very early memory T cells (T _VEM ) in patients with granulomatosis with polyangiitis (GPA). Percentages of CCR7⁺CD45RA^med T_VEM and CCR7⁺CD45RA^high T_N in the CD4⁺ T cell population are shown. Percentages of positive cells were assessed by flow cytometry. Values are presented as mean ± standard error of the mean. **P < 0.01, Mann-Whitney U test. CCR, CC chemokine receptor; HC, healthy control.