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Table 4 Results from multiple linear regression analyses with BMD at different measuring sites as the outcome.

From: Osteoporosis in ankylosing spondylitis - prevalence, risk factors and methods of assessment

  AP lumbar aBMD Lateral lumbar aBMD Lumbar
vBMD
Total hip
aBMD
Femoral neck aBMD Total radius aBMD
Constant
all variables
0.829   0.539   0.2390   0.783   0.654   0.625  
R2 all variables 0.290   0.245   0.266   0.402   0.343   0.591  
R2 for demographic variables 0.254   0.163   0.171   0.338   0.279   0.569  
R2 for disease related variables 0.079   0.181   0.276   0.174   0.198   0.253  
Demographic variables B P-value B P-value B P-value B P-value B P-value B P-value
Sex NA   NA   NA   -0.056 0.009 NA   -0.082 < 0.001
Age, years NA   NA   NA   NA   NA   -0.001 0.002
Menopause -0.156 < 0.001 -0.104 < 0.001 NA   -0.053 0.048 -0.076 < 0.001 -0.035 0.009
BMI, kg/m2 0.014 < 0.001 NA   NA   0.014 < 0.001 0.011 < 0.001 0.004 < 0.001
Disease-related variables B P -value B P -value B P -value B P -value B P -value B P -value
Years since diagnosis NA   -0.003 < 0.001 NA   NA   NA   NA  
Years since symptom debut NA   NA   -0.001 < 0.001 -0.002 0.019 -0.002 0.028 NA  
BASMI NA   NA   -0.006 < 0.001 -0.023 < 0.001 -0.029 < 0.001 -0.008 0.016
Hemoglobin NA   0.002 0.008 NA   NA   NA   NA  
WBC NA   NA   NA   -0.007 0.05 NA   NA  
PLT 0.000 0.003 NA   NA   NA   NA   NA  
  1. All demographic and disease-related variables that were significantly correlated with BMD in the first analyses were entered as covariates. The table shows only covariates that remained significantly associated with BMD in the stepwise multiple linear regression models. Coding for categorical variables, 1 = yes, 0 = no; for sex, 1 = woman, 2 = man. Beta values are unstandardized regression coefficients.
  2. AP, anteroposterior; BASMI, Bath Ankylosing Spondylitis Metrology Index; aBMD, areal bone mineral density; vBMD, volumetric BMD; BMI, body mass index; mSASSS, modified Stoke Ankylosing Spondylitis Spine Score; PLT, platelet count; WBC, white blood cell count.