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Table 1 Baseline characteristics and 5-year outcome of patients who will satisfy cumulatively 1987 ACR criteria for rheumatoid arthritis at any time during the first 5 years of follow-up, versus those who will not

From: Long-term stability of anti-cyclic citrullinated peptide antibody status in patients with early inflammatory polyarthritis

Classification Satisfying 1987 ACR criteria within the first 5 years
(n= 463; 72%)
NEVER satisfying 1987 ACR criteria within the first 5 years (n= 177; 28%) P value
Baseline characteristics    
Age (onset) 55.4 (45.8, 65.4) 47.7 (34.3, 57.9) 3.6E-09
Female 305 (66%) 114 (64%) 0.73
Symptom duration 5.3 (2.6, 11.3) 4.5 (1.9, 9.0) 0.01
Anti-CCP +ve 187 (40.4%) 8 (4.5%) 1.2E-18
Anti-CCP titer 1.6 (0.7, 42.5) 0.8 (0.5, 1.4) 6.4E-16
HAQ 0.875 (0.375, 1.5) 0.25 (0, 0.625) 5.8E-24
DAS28 4.4 (3.5, 5.4) 2.8 (2.1, 3.6) 5.2E-33
5-year outcome    
HAQ 1.125 (0.375, 1.75) 0.25 (0, 0.625) 4.1E-24
DAS28 2.8 (2.0, 3.9) 2.0 (1.15, 2.4) 1.3E-14
Erosions 220 (56.9%) 12 (8.8%) 3.1E-22
Larsen score 12 (2, 31) 1 (0, 4) 9.3E-21
DMARD received 278 (60.0%) 23 (13.1%) 2.2E-26
  1. Continuous variables expressed as median (interquartile range) and compared by using the Mann-Whitney U test. Categoric variables expressed as number (percentage) and compared by using the χ2 test. ACR, American College of Rheumatology criteria for rheumatoid arthritis; DAS, disease activity score; HAQ, Health Assessment Questionnaire.