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Table 3 Sensitivity, specificity and likelihood ratios for presence of radiographic damage and functional disability at 5 years according to baseline and 5-year autoantibody status

From: Long-term stability of anti-cyclic citrullinated peptide antibody status in patients with early inflammatory polyarthritis

Autoantibody status Erosions Larsen score > 15 HAQ ≥ 1
  Sensitivity Specificity Accuracy LR Sensitivity Specificity Accuracy LR Sensitivity Specificity Accuracy LR
Anti-CCP+             
Baseline 0.56 0.89 0.74 5.0 0.65 0.85 0.79 4.3 0.41 0.78 0.61 1.8
Year 5 0.56 0.89 0.75 5.1 0.66 0.86 0.79 4.5 0.41 0.78 0.61 1.8
Base or Year 5 0.59 0.88 0.75 5.1 0.69 0.85 0.79 4.5 0.43 0.77 0.62 1.8
RF +             
Baseline 0.44 0.84 0.67 2.8 0.50 0.82 0.71 2.7 0.36 0.77 0.59 1.6
Year 5 0.40 0.84 0.65 2.5 0.42 0.81 0.68 2.2 0.36 0.82 0.61 1.9
Base or Year 5 0.54 0.76 0.67 2.3 0.60 0.74 0.69 2.3 0.45 0.72 0.60 1.6
  1. Logistic regression model; LR, likelihood ratio.