Long-term stability of anti-cyclic citrullinated peptide antibody status in patients with early inflammatory polyarthritis

Table 5 Logistic regression for 5-year radiographic damage according to categories of baseline anti-CCP titer

Anti-CCP titer	Erosions					Larsen score ≥ 15
	No with erosions/total in group (%)	OR (95% CI)	P value	Adjusted OR (95% CI)^a	P value^a	No with Larsen ≥ 15/total in group (%)	OR (95% CI)	P value	Adjusted OR (95% CI)^a	P value^a
≤ 2	85/324 (26%)	Ref	-	Ref	-	47/323 (15%)	Ref	-	Ref	-
> 2 to 5	14/25 (56%)	3.6 (1.5, 8.3)	0.003	3.4 (1.2, 9.8)	0.02	11/25 (44%)	4.6 (1.9, 11)	0.0001	4.3 (1.4, 13)	0.009
> 5 to 20	16/22 (73%)	7.5 (2.7, 20)	< 0.0001	3.8 (1.3, 12)	0.02	14/22 (64%)	10.3 (3.9, 27)	< 0.0001	5.3 (1.7, 16)	0.003
> 20	94/116 (81%)	12.4 (6.6, 22)	< 0.0001	9.0 (4.4, 18)	< 0.0001	77/115 (67%)	11.9 (6.7, 21)	< 0.0001	9.7 (4.7, 20)	< 0.0001

^aAdjusted for age, gender, symptom duration and CRP, RF, HAQ, and swollen- and tender-joint counts at baseline. CI, confidence interval; OR, odds ratio.

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