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Figure 1 | Arthritis Research & Therapy

Figure 1

From: Serum amyloid A triggers the mosodium urate -mediated mature interleukin-1β production from human synovial fibroblasts

Figure 1

SAA induces the transcription of pro-IL-1β in human synovial fibroblasts. A. Synovial fibroblasts were incubated with SAA (2 μg/ml) for the indicated periods. The cells were harvested and analyzed for pro-IL-1β mRNA levels by real-time PCR. B. Synovial fibroblasts were incubated with the indicated concentrations of SAA for 6 h. The cells were harvested and analyzed for IL-1β and GAPDH mRNA levels by real-time PCR. Values represent the mean ± SD of three independent experiments.*P <0.001 compared to SAA-untreated synovial fibroblasts.

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Arthritis Research & Therapy

ISSN: 1478-6362

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