Semaphorin 3A is a marker for disease activity and a potential immunoregulator in systemic lupus erythematosus

Table 1 Clinical characteristics of SLE patients

	SLEDAI	Sema3A (ng/ml)	a. Cal	LN	a. dsDNA	Complement		Treatment
						C3	C4
1	16	44		+	+	L	L	HCQ; P
2	14	32	+	+	+	L	L	HCQ; P
3	3	82				N	N	HCQ
4	4	63				N	L	P
5	4	69	+			N	N	HCQ; P; AZA
6	4	51	+			N	N	HCQ; Atabrin
7	5	69			+	N	L	HCQ; P
8	8	53				N	L	HCQ; P; AZA
9	6	79	+		+	L	L	HCQ; P; AZA
10	12	44				N	L	HCQ; P; AZA
11	6	65				N	N	HCQ; P
12	9	48			+	N	L	HCQ; P; AZA
13	6	65	+		+	L	L	HCQ; P; AZA
14	3	76				N	L	HCQ; P
15	12	42	+		+	N	L	HCQ; P; AZA
16	8	64	+		+	L	L	HCQ; P;
17	18	38	+	+	+	L	L	HCQ; P; AZA
18	18	33	+	+	+	L	L	HCQ; P; MTX; IVIg
19	4	68			+	N	L	HCQ; P; AZA
20	6	55				N	N	HCQ; P
21	6	60	+		+	N	L	HCQ; P
22	24	20	+	+	+	L	L	HCQ; P; MTX; IVIg
23	5	70	+			N	N	HCQ; P
24	10	50	+	+	+	L	L	HCQ; P; AZA
25	13	36	+	+	+	L	L	HCQ; P;
26	4	65			+	N	N	HCQ;
27	26	26	+	+	+	L	L	HCQ; P; CYC
28	6	61				N	N	HCQ; P; AZA
29	4	63				N	N	HCQ; P; AZA
30	4	59				N	L	HCQ
31	5	58	+		+	N	N	HCQ; P; AZA
32	20	34	+	+	+	L	L	HCQ; P; CYC

a.Cal, anti-cardiolipin; a.dsDNA, anti-double-stranded DNA; AZA, azathioprine; CYC, cyclophosphamide; F, female; HCQ, hydroxychloroquine; IVIg, intravenous immunoglobulin; L, low; LN, lupus nephritis; M, male; MTX, Methotrexate; N, normal; P, prednisone; Sema3A, semaphorin 3A.

ISSN: 1478-6362