Characterization of new bone formation in gout: a quantitative site-by-site analysis using plain radiography and computed tomography

Table 3 Site-by-site CT analysis.

		Erosion present, number	Erosion absent, number	OR (95%CI)	P	Erosion diameter, in eroded joints, mean (SD)	P	Tophus present, number	Tophus absent, number	OR (95%CI)	P	Tophus diameter, in joints with IO tophus, mean (SD)	P
Spur	Present	127	14	45.1	<0.0001	7.0 (3.7)	<0.0001	121	20	48.4	<0.0001	10.9 (7.9)	0.02
	Absent	110	547	(25.0-81.3)		4.5 (3.0)		73	584	(28.4-82.4)		8.2 (6.7)
Osteophyte	Present	116	127	3.3	<0.0001	5.6 (3.2)	0.27	99	144	3.3	<0.0001	8.4 (5.3)	0.006
	Absent	121	434	(2.4-4.5)		6.1 (3.9)		95	460	(2.4-4.7)		11.3 (9.1)
Periosteal NBF	Present	41	7	16.6	<0.0001	7.2 (4.4)	0.0005	38	10	14.5	<0.0001	10.4 (7.9)	0.65
	Absent	196	554	(7.3-37.5)		5.5 (3.3)		156	594	(7.1-27.0)		9.7 (7.5)
Ankylosis	Present	5	0	26.6	0.002	8.3 (3.1)	0.11	5	0	35.1	0.0008	10.7 (7.3)	0.80
	Absent	232	561	(1.5-482.7)		5.8 (3.8)		189	604	(1.9-638.0)		9.8 (7.6)
Sclerosis	Present	179	49	32.3	<0.0001	6.5 (3.8)	<0.0001	161	67	39.1	<0.0001	10.4 (7.9)	0.03
	Absent	58	512	(21.3-48.9)		3.9 (2.0)		33	537	(24.9-61.5)		7.3 (4.6)

Relationship of new bone formation (NBF) with erosion and intraosseous tophus on CT (n = 798 joints). CI, confidence interval; CT, computed tomography; OR, odds ratio; SD, standard deviation.

ISSN: 1478-6362