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Figure 4 | Arthritis Research & Therapy

Figure 4

From: Carbonic anhydrase I (CA1) is involved in the process of bone formation and is susceptible to ankylosing spondylitis

Figure 4

Expression of CA1 in Saos-2 cells. The expression of CA1 in Saos-2 cells was determined by (A) western blotting and (B) real-time PCR. The expression levels were normalized to the expression of GAPDH. The transcription and translation of CA1 were significantly increased in Saos-2 cells cultured in the presence of OM, but decreased when the cells were incubated with 100 μM acetazolamide (AZ). This experiment was repeated three times and similar results were obtained. * P < 0.05, ** = P < 0.01, *** = P < 0.001. OM, osteogenic medium.

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Arthritis Research & Therapy

ISSN: 1478-6362

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