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Figure 3 | Arthritis Research & Therapy

Figure 3

From: IL-1ra delivered from poly(lactic-co-glycolic acid) microspheres attenuates IL-1β-mediated degradation of nucleus pulposus in vitro

Figure 3

Mechanical properties of nucleus pulposus constructs ( n = 5) treated with IL-1β or IL-1ra conditioned media or both were evaluated in confined compression. (a) Aggregate modulus (HA). (b) Hydraulic permeability (k0). Values are mean ± standard deviation. *P < 0.05 versus untreated constructs; P < 0.05 versus IL-1β-only treated constructs. IL-1β, interleukin-1 beta; IL-1ra, interleukin-1 receptor antagonist; N.s., Newton second.

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