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Table 3 Endothelial, T-cell and fibroblast activation markers in early SSc, UCTD patients and controls

From: Early systemic sclerosis: short-term disease evolution and factors predicting the development of new manifestations of organ involvement

Biomarker Early SSc (n= 21) UCTD (n= 24) Controls† (n= 25)
sE-selectin (pg/ml) median (range) 0.732 (0.35 to 1.2) 0.87 (0.32 to 1.99) # 0.806 (0.4 to 1.76)
sIL-2Rα (pg/ml) median (range) 239 (66.7 to 1,002) 346 (14.3 to 931) 301 (17.9 to 807)
ICTP (μg/l) median (range) 3.998 (1.88 to 10.5)*; ° 2.86 (1.17 to 4.25) 3.21 (1.39 to 5.27)
PIIINP (μg/l) median (range) 1.491 (0.002 to 5.43) 1.66 (0.01 to 2.98) 1.65 (0.35 to 7.49)
  1. ICTP, carboxyterminal telopeptide of type I collagen; IL-2Rα, interleukin-2 receptor alpha; PIIINP, aminoterminal propeptide of type III collagen; s, soluble; SSc, systemic sclerosis; UCTD, undifferentiated connective tissue disease. † Affected by osteoarthritic or primary fibromyalgia syndrome. * P < 0.05 early SSc vs controls;°P < 0.05 early SSc vs UCTD; #P < 0.05 UCTD vs early SSc (P = 0.07 vs controls)