Table 4 Clinical outcomes by duration of breastfeeding
From: Early menopause and severity of rheumatoid arthritis in women older than 45 years
Breastfeeding 0 months (n= 43) a | Breastfeeding 1-12 months (n= 72) a | Breastfeeding > 12 months (n= 19) a | |
|---|---|---|---|
Mean age at diagnosis; years (SD) | 63.6 (8.37) | 62.8 (8.30) | 64.2 (8.27) |
Mean follow-up time; years (SD) | 9.6 (3.4) | 10.3 (3.7) | 10.5 (2.8) |
> 3 DMARDs used (%) | 8/43(18.6) | 17/71 (23.9) | 5/19 (26.3) |
DMARDs in combination (%) | 14/43 (32.6) | 32/71 (45.1) | 8/19 (42.1) |
Biological treatment ever (%) | 10/43(23.3) | 21/71 (29.6) | 6/19 (31.6) |
Documented radiographic erosions (ever) (%) | 25/39 (64.1) | 36/70 (51.4) | 10/16 (62.5) |
RF positive (%) | 28/43 (65.1) | 53/71 (74.6) | 13/18 (72.2) |
Mean HAQ at diagnosis (CI)b | 0.91 (0.64-1.18) (n = 21) | 0.89 (0.69-1.09) (n = 39) | 0.86 (0.47-1.25) (n = 10) |
Mean HAQ 1 year after diagnosis (CI)b | 0.76 (0.49-1.03) (n = 24) | 0.86 (0.66-1.06) (n = 44) | 0.68 (0.32-1.03) (n = 14) |
Mean HAQ 5 years after diagnosis (CI)b | 0.91 (0.68-1.14) (n = 31) | 0.90 (0.72-1.09) (n = 49) | 0.85 (0.48-1.22) (n = 12) |
Mean HAQ 10 years after diagnosis (CI)b | 0.78 (0.50-1.06) (n = 16) | 0.94 (0.76-1.13) (n = 38) | 1.08 (0.70-1.45) (n = 9) |
Cluster distribution (P = 0.88) | |||
Severe RA (%) | 8/31 (25.8) | 15/48 (31.2) | 3/11 (27.3) |
Mild/moderate seropos RA (%) | 13/31 (41.9) | 20/48 (41.7) | 6/11 (54.5) |
Mild/moderate seroneg RA (%) | 10/31 (32.3) | 13/48 (27.1) | 2/11 (18.2) |