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Table 4 Clinical outcomes by duration of breastfeeding

From: Early menopause and severity of rheumatoid arthritis in women older than 45 years

  Breastfeeding 0 months
(n= 43) a
Breastfeeding 1-12 months
(n= 72) a
Breastfeeding > 12 months
(n= 19) a
Mean age at diagnosis; years (SD) 63.6 (8.37) 62.8 (8.30) 64.2 (8.27)
Mean follow-up time; years (SD) 9.6 (3.4) 10.3 (3.7) 10.5 (2.8)
> 3 DMARDs used (%) 8/43(18.6) 17/71 (23.9) 5/19 (26.3)
DMARDs in combination (%) 14/43 (32.6) 32/71 (45.1) 8/19 (42.1)
Biological treatment ever (%) 10/43(23.3) 21/71 (29.6) 6/19 (31.6)
Documented radiographic erosions (ever) (%) 25/39 (64.1) 36/70 (51.4) 10/16 (62.5)
RF positive (%) 28/43 (65.1) 53/71 (74.6) 13/18 (72.2)
Mean HAQ at diagnosis (CI)b 0.91 (0.64-1.18) (n = 21) 0.89 (0.69-1.09) (n = 39) 0.86 (0.47-1.25) (n = 10)
Mean HAQ 1 year after diagnosis (CI)b 0.76 (0.49-1.03) (n = 24) 0.86 (0.66-1.06) (n = 44) 0.68 (0.32-1.03) (n = 14)
Mean HAQ 5 years after diagnosis (CI)b 0.91 (0.68-1.14) (n = 31) 0.90 (0.72-1.09) (n = 49) 0.85 (0.48-1.22) (n = 12)
Mean HAQ 10 years after diagnosis (CI)b 0.78 (0.50-1.06) (n = 16) 0.94 (0.76-1.13) (n = 38) 1.08 (0.70-1.45) (n = 9)
Cluster distribution (P = 0.88)    
   Severe RA (%) 8/31 (25.8) 15/48 (31.2) 3/11 (27.3)
   Mild/moderate seropos RA (%) 13/31 (41.9) 20/48 (41.7) 6/11 (54.5)
   Mild/moderate seroneg RA (%) 10/31 (32.3) 13/48 (27.1) 2/11 (18.2)
  1. CI, confidence interval; HAQ, Health Assessment Questionnaire; RF, rheumatoid factor; SD, standard deviation. aIn case of missing data, numbers (n) indicated for each variable. bAdjusted for age at diagnosis.