Figure 3

Correlation between in vitro and in vivo glucocorticoid sensitivity in intramuscularly treated RA patients. In vivo glucocorticoid sensitivity is presented as percentage improvement in DAS according to the following formula: $100\times \frac{DAS,baseline-DAS,after2weeks}{DAS,baseline}$

Correlations between √IL-2-EC₅₀ values (A), GILZ-EC₅₀ values (B), natural logarithm of the number of GRs per cell (C), and natural logarithm of the K_D of the receptor (D) and percentage improvement DAS. R², square of the Pearson correlation coefficient; proportion explained variability. Triangles (▲) represent the tREACH patients, and solid circles (●) represent FLARE patients.