Evolution of peripheral blood lymphocytes with vitamin D supplementation. Time evolution of the proportion and the absolute number of CD3+ T cells, CD4+ and CD8+ T cells, CD19+ B cells and CD3-CD56+ NK cells. At 2 and 6 months, the proportion and absolute number of CD3+ T cells, CD4+ and CD8+ T cells and CD3-CD56+ NK cells remained stable, while the CD19+ B cell frequency and count significantly decreased at 2 months. Mean ± standard error of the mean (SEM) is shown. *P < 0.05 versus Day 0; Wilcoxon test.