Supplementary Table 1 The sequence for the designed Tie receptors and ligands

Ang-1

GCC ATT ACC AGT CAG AGG CAG T

CAT GCT AAG AAT TGA GTT AAT

AAT AGG CTC GGT TCC CTT CC

Ang-2

CGC TCG AAT ACG ATG ACT CG

TGC AGA GGC TGC AAG TGC TGG AGA A

CCA CTG AGT GTT GTT TTC CAT GAT

Tie1

GCC ACG TTC TGG CTG GAT

TCA GGC CTC CTC AGC TGT GGC AT

ACT TCA CTT ACG CGG GCA TT

Tie2

GGC AAC TTG ACT TCG GTG CT

ACT TAC ATC CCA GGG AGC AGT ACG TGG TC

GGC CTT GGT GTT GAC TCT AGC T