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Figure 1 | Arthritis Research & Therapy

Figure 1

From: Modulating proximal cell signaling by targeting Btk ameliorates humoral autoimmunity and end-organ disease in murine lupus

Figure 1

PCI-32765 dampens the production of anti-nuclear autoantibodies in B6.Sle1 mice. The indicated autoantibody ELISAs were performed on sera isolated at the indicated day of treatment from mice either treated with PCI-32765 (black bars, n = 5) or a vehicle (grey bars, n = 4). All values are the optical density (OD) readings at 405 nm wavelength. *P < 0.05, **P < 0.01 compared to day-0 values measured in the same mice. D0, day zero; D56, day 56.

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Arthritis Research & Therapy

ISSN: 1478-6362

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