PCI-32765 dampens the production of anti-nuclear autoantibodies in B6.Sle1 mice. The indicated autoantibody ELISAs were performed on sera isolated at the indicated day of treatment from mice either treated with PCI-32765 (black bars, n = 5) or a vehicle (grey bars, n = 4). All values are the optical density (OD) readings at 405 nm wavelength. *P < 0.05, **P < 0.01 compared to day-0 values measured in the same mice. D0, day zero; D56, day 56.