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Table 2 Circulating levels of tenascin-C (TNC) are raised in a number of inflammatory conditions

From: Raised circulating tenascin-C in rheumatoid arthritis

Sample Mean TNC
(ng/ml)
Number of samples P-value
(compared to N)
Patients with abnormal TNC, %
Normal healthy subjects (N) 20.7
(95% CI = 33)
19   
Rheumatoid arthritis (RA) 118.2 40 < 0.0001 82.5
Systemic lupus erythmatosus (SLE) 77.8 24 < 0.0001 83.3
Sjogren's syndrome (SS) 16.7 24 0.3489 8.3
Idiopathic inflammatory myositis (IIM) 69.8 25 0.0008 64.0
Psoriatic arthritis (PSA) 64.7 6 0.0026 100.0
Ankylosing spondylitis (AS) 53.8 13 0.0006 76.9
  1. Blood was taken from normal healthy controls (N) and patients with RA, SLE, SS, IIM, PSA and AS, and TNC levels were determined in serum by ELISA. The 95% confidence interval (CI) of TNC levels in normal healthy subjects was determined to be 33 ng/ml. The P-value was determined by Student's t-test.