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Table 4 Allelic frequencies of the major haplotypes found in RA patients and controls

From: Association of the AIRE gene with susceptibility to rheumatoid arthritis in a European population: a case control study

Haplotypes Controls
2n= 942
Patients
2n= 930
P-value P c- value* Odds ratio (95% CI)
rs2776377 rs878081 rs2075876 rs1055311      
A C G C 0.324 0.331 ns   1.03 (0.85, 1.24)
A C G T 0.182 0.193 ns   1.09 (0.86, 1.38)
G T G C 0.174 0.124 0.0025 0.0141 0.67 (0.52, 0.87)
G C G C 0.110 0.146 0.0182 ns 1.38 (1.05, 1.82)
G C A C 0.106 0.111 ns   1.05 (0.78, 1.40)
A T G C 0.076 0.065 ns   0.84 (0.59, 1.20)
  1. RA, rheumatoid arthritis; ns, not significant at P > 0.05. *P c -value, 10,000-fold permutation testing.