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Table 4 Allelic frequencies of the major haplotypes found in RA patients and controls

From: Association of the AIRE gene with susceptibility to rheumatoid arthritis in a European population: a case control study

Haplotypes

Controls

2n= 942

Patients

2n= 930

P-value

P c- value*

Odds ratio (95% CI)

rs2776377

rs878081

rs2075876

rs1055311

     

A

C

G

C

0.324

0.331

ns

 

1.03 (0.85, 1.24)

A

C

G

T

0.182

0.193

ns

 

1.09 (0.86, 1.38)

G

T

G

C

0.174

0.124

0.0025

0.0141

0.67 (0.52, 0.87)

G

C

G

C

0.110

0.146

0.0182

ns

1.38 (1.05, 1.82)

G

C

A

C

0.106

0.111

ns

 

1.05 (0.78, 1.40)

A

T

G

C

0.076

0.065

ns

 

0.84 (0.59, 1.20)

  1. RA, rheumatoid arthritis; ns, not significant at P > 0.05. *P c -value, 10,000-fold permutation testing.
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Arthritis Research & Therapy

ISSN: 1478-6362

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