Table 4 Comparison of renal pathological data between lupus nephritis patients with and without renal TMA

Number of biopsies

36

112

Class II (%)

0 (0)

5 (4.5)

0.336

Class III (%)

3 (8.3)

26 (23.2)

0.05

Class IV (%)

30 (83.3)

65 (58.0)

0.006

Class V (%)

3 (8.3)

16 (14.3)

0.567

AI score (mean ± SD)

10.78 ± 4.16

7.58 ± 4.29

<0.001

Endocapillary hypercellualrity (mean ± SD)

2.78 ± 0.59

2.20 ± 0.99

<0.001

Cellular crescents (mean ± SD)

2.06 ± 1.94

1.38 ± 1.8

0.055

Karyorrhexis/fibrinoid necrosis (mean ± SD)

1.28 ± 1.06

0.95 ± 1.18

0.137

Subendothelial hyaline deposits (mean ± SD)

1.72 ± 1.09

1.10 ± 1.07

0.003

Interstitial inflammation (mean ± SD)

1.63 ± 0.83

1.19 ± 0.72

0.005

Glomerular leukocyte infiltration (median; inter-quartile range)

1

1, 2

1

0, 1

0.006

CI score (mean ± SD)

3.67 ± 1.91

2.80 ± 2.15

0.033

Glomerular sclerosis (mean ± SD)

0.53 ± 0.70

0.48 ± 0.70

0.733

Fibrous crescents (median; inter-quartile range)

0

0, 1

0

0, 0

0.166

Tubular atrophy (mean ± SD)

1.47 ± 0.61

1.06 ± 0.77

0.004

Interstitial fibrosis (mean ± SD)

1.36 ± 0.59

1.02 ± 0.79

0.018