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Table 1 Demographics and disease-related characteristics of patients and controls

From: Impaired beta cell function is present in nondiabetic rheumatoid arthritis patients

 

Rheumatoid arthritis (n= 101)

Controls (n= 99)

P a

  

GC-RA (n= 46)

GC+RA (55)

P b

  

Age, years

55.2 ± 10.0

53.0 ± 10.1

57.1 ± 9.7

0.04a

55.1 ± 10.6

0.90

Female, n (%)

86 (85)

38 (67)

48 (87)

0.51

90 (91)

0.21

Body mass index, kg/m2

29.5 ± 5.9

27.8 ± 4.8

30.0 ± 6.6

0.18

29.5 ± 5.4

0.59

Hip circumference, cm

106 (99-118)

105 (97-115)

109 (99-118)

0.17

102 (98-110)

0.23

Waist circumference male, cm

106 ± 17

105 ± 12

107 ± 22

0.79

100 ± 12

0.57

Waist circumference female, cm

96 ± 15

92 ± 14

98 ± 15

0.13

91 ± 11

0.12

Waist-to-hip ratio

0.90 (0.85-0.94)

0.89 (0.83-0.94)

0.90 (0.86-0.94)

0.34

0.86 (0.80-0.92)

0.71

Hypertension, n (%)

36 (38)

14 (25)

22 (40)

0.51

31 (31)

0.34

Statins intake, n (%)

29 (30)

13 (23)

16 (29)

0.78

28 (28)

0.77

Metabolic syndrome, n (%)

32 (37)

15 (27)

17 (31)

0.96

18 (18)

0.11

ESR, mm/h

25 (16-39)

25 (15-41)

26 (18-39)

0.70

18 (13-25)

0.00a

CRP, mg/dl

3.8 (1.4-9.4)

4.5 (1.3-13.7)

3.2 (1.6-9.0)

0.59

2.0 (0.9-4.7)

0.00a

Cholesterol, mg/dl

210 ± 40

203 ± 30

216 ± 46

0.18

207 ± 39

0.62

Triglycerides, mg/dl

118 (85-151)

110 (81-139)

121 (91-152)

0.28

102 (69-133)

0.00a

HDL cholesterol, mg/dl

59 ± 15

58 ± 14

60 ± 16

0.48

56 ± 14

0.13

LDL cholesterol, mg/dl

127 ± 33

127 ± 28

127 ± 37

0.89

129 ± 34

0.62

Disease duration, years

7.5 ± 5.8

8.7 ± 4.5

6.2 ± 6.8

0.08

  

DAS28-ESR

3.99 ± 1.41

4.11 ± 1.56

3.18 ± 1.27

0.45

  

HAQ

0.61 (0.24-1.28)

0.69 (0.13-1.37)

0.55 (0.2-1.23)

0.92

  

Positive rheumatoid factor, n (%)

64 (65)

21 (38)

43 (78)

0.00a

  

Current nonbiologic DMARD, n (%)

88 (87)

41 (73)

47 (85)

0.58

  

Current prednisone, n (%)

55 (54.5)

     

Prednisone, average mg/day/3 months

6.24 ± 2.54

     
  1. aComparison between controls and patients; P value < 0.05. bComparison between not-taking-corticoids and taking-corticoids patients. Data expressed as mean (± standard deviation) or median (interquartile range). Dichotomous variables are expressed as n and percentage. CRP, C-reactive protein; DAS28, Disease Activity Score; DMARD, disease-modifying antirheumatic drug; ESR, erythrocyte sedimentation rate; GC-RA, RA patients not taking corticosteroids; GC+RA, RA patients taking prednisone. HAQ, Health Assessment Questionnaire; HDL, high-density lipoprotein; LDL, low-density lipoprotein.
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Arthritis Research & Therapy

ISSN: 1478-6362

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