Figure 2

FR-binding affinities. (A) Displacement of folate-FITC binding from human KB cells (10 nM, 4ºC) with increasing concentrations of unlabelled folic acid, fluoro-PEG-folate and 5-Me-THF. (B) Relative binding affinities to FR of folic acid (set at 1) versus fluoro-PEG-folate and 5-Me-THF. Results are presented in mean ± SEM of seven separate experiments.