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Table 1 Demographic data and clinical characteristics of patients with adult-onset Still's disease (AOSD), patients with systemic lupus erythematosus (SLE) and healthy controls (HC)

From: Involvement of TLR7 MyD88-dependent signaling pathway in the pathogenesis of adult-onset Still's disease

Characteristics

AOSD

(n= 28)

SLE

(n= 28)

HC

(n= 12)

Age at study entry, years

37.4 ± 14.8

38.2 ± 8.7

36.4 ± 9.2

Proportion of females

20 (71.4%)

25 (89.3%)

8 (66.7%)

Fever (≧39°C)

28 (100%)

24 (85.8%)

NA

Rash

25 (89.3%)

21 (75.0%)

NA

Arthritis

20 (71.4%)

15 (53.6%)

NA

Lymphadenopathy

7 (25.0%)

6 (21.4%)

NA

Nephritis

0 (0.0%)

9 (32.1%)*

NA

Ferritin levels, μg/L

931.0 ± 106.5

NA

NA

AOSD activity score

5.93 ± 1.46

NA

NA

SLEDAI

N A

7.8 ± 2.3

NA

C3 levels, mg/dL

NA

84.6 ± 24.7

NA

C4 levels, mg/dL

NA

19.5 ± 8.9

NA

Anti-ds DNA, U/mL

NA

183.2 ± 200.3

NA

  1. Data are presented as mean ± SD or number (percentage); NA, not applicable. Nephritis is defined by persistent proteinuria (>0.5 g/24 hours), the presence of cellular casts, or pathological examination of renal biopsy specimens showing lupus nephritis. C3 and C4, complement 3 and 4; Anti-ds DNA, anti-double strand DNA antibody; SLEDAI, SLE disease activity index; *P <0.001, versus AOSD patients.