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Table 1 Tests used to define neurocognitive dysfunction

From: Functional neuronal network activity differs with cognitive dysfunction in childhood-onset systemic lupus erythematosus

Domain Measure Source Description
Working memory Digit span Age-appropriate Wechsler intelligence scale [32, 33] Ability to repeat back in order, or in a re-sequenced order, increasingly difficult strings of numbers
  Letter-number sequencing Age-appropriate Wechsler intelligence scale [32, 33] Ability to mentally re-sequence a series of letters and numbers before repeating them back
Psychomotor speed Coding Age-appropriate Wechsler intelligence scale [32, 33] Test-takers decode and transcribe a series of symbols as quickly as possible
  Symbol search Age-appropriate Wechsler intelligence scale [32, 33] Score reflects speed and accuracy of test-takers' visual searches for matches in rows of symbols
Attention Hit reaction time standard error Conners' continuous performance test II [34] On a 15-minute-long boring task, the variability in reaction time to specific letters flashing on screen
  Inhibition vs. color naming score Delis-Kaplan executive functioning system [35] Relative ability to focus on the color of the ink in which a conflicting color word is printed (for example, 'blue' written in red ink).
Visuoconstructional abilities Block design Wechsler abbreviated scales of intelligence [36] Ability to efficiently reproduce colored line drawings using blocks with sides that have varying patterns
  Block counting Kaufman assessment battery for children [37, 38] Ability to mentally represent the volume of a three-dimensional block construction printed in two-dimensional space