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Figure 2 | Arthritis Research & Therapy

Figure 2

From: B lymphocytopenia in rheumatoid arthritis is associated with the DRB1 shared epitope and increased acute phase response

Figure 2

B-cell counts in the peripheral circulation of 70 prospectively followed rheumatoid arthritis (RA) patients determined after a mean disease duration of 4.4 years. Absolute numbers of CD19+ B cells are depicted to exclude shifts in the B-cell/T-cell ratio of patients expressing the RA-associated shared epitope on a DR4 allele (SE DR4+), of patients expressing DR1 but not a RA-associated DR4 allele (SE DR1+), and of patients negative for the SE (SE-negative). Box plots depict the median and interquartile range.

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