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Figure 2 | Arthritis Research & Therapy

Figure 2

From: Adenosine A2A receptors promote collagen production by a Fli1- and CTGF-mediated mechanism

Figure 2

Adenosine A 2A receptor occupancy inhibits nuclear Fli1 protein expression in human dermal fibroblasts. NHDF cells were incubated with CGS-26180 at 1 to 10 µM over 24 hours and cellular fractionation was performed as described under "Methods". A) Representative Western-blot images showing Fli1 and the nuclear marker p84. B) Bands were quantified and data represent means ± S.E.M. from three independent experiments. Statistics were performed by one-way ANOVA with post-hoc analysis by Newman-Keuls test, *P <0.05 vs. non-stimulated control.

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