Analysis of immunoglobulin light chain rearrangements in the salivary gland and blood of a patient with Sjögren's syndrome

Table 5 Contribution of mutations of RGYW/WRCY sequences to all mutations (%) in V_L gene rearrangements of B cells from the peripheral blood and from the parotid gland of a patient with Sjögren's syndrome (SS), and of peripheral blood B cells from normal healthy subjects (NHS)

Significant difference of the contribution of mutations of RGYW/WRCY sequences to all mutations comparing nonproductive and productive Vλ gene rearrangements: ^*P = 0.018 (chi-square test), peripheral blood B cells from the patient with SS; ^†P = 0.049, B cells from the parotid gland; and ^‡P < 0.0001, B cells from the peripheral blood of NHS [27].

ISSN: 1478-6362