IgG subclass antibodies to human and bacterial HSP60 are not associated with disease activity and progression over time in axial spondyloarthritis

Table 3 Statistical differences in IgG1 or IgG3 levels between SpA patients (n = 39) and healthy controls (n = 39) against six different antigens

Antigen	IgG1		IgG3
	2006	2010	2006	2010
Human HSP60	0.0082**	0.0004***	0.0001***	0.0022**
Salmonella enterica Enteritidis HSP60	0.0008***	0.0002***	0.8455	0.2782
Chlamydia trachomatis HSP60	0.9164	0.7453	0.0932	0.8338
Campylobacter jejuni HSP60	0.0451	0.1109	0.9482	0.5587
Chlamydia pneumoniae	0.3738	0.4211	0.0892	0.3748
Chlamydia trachomatis	0.0089**	0.0786	0.2693	0.4010

SpA: spondyloarthritis, HC: healthy control. The Mann-Whitney rank-sum test was used to compare the SpA cohort group (2006 and 2010) with healthy controls. Ig, immunoglobulin. ***P < 0. 001. **P < 0.01.

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