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Table 4 Logistic multivariate regression to detect independent associations between anti-FOXE3p53-62 Ab levels and clinical and laboratory parameters (continuous and dichotomized) in 75 ACA+ patients

From: Clinical correlates of a subset of anti-CENP-A antibodies cross-reacting with FOXE3p53-62 in systemic sclerosis

Variable B coefficient Exp (B) P-valuea 95% CI
Gender -0.065 1.067 0.956 0.104, 0.914
Age at diagnosis -0.022 0.978 0.465 0.922, 1.038
Disease duration 0.039 1.040 0.661 0.943, 1.096
mRss -0.06 0.942 0.277 0.846, 1.049
ESR 0.004 1.004 0.847 0.962, 1.049
CRP -0.052 0.949 0.749 0.689, 1.307
ANA titer 0.000 1.000 0.550 0.999, 1.002
Anti-Ap1-17 IgG 0.00 1.000 0.678 0.999, 1.001
Anti-Ap17-30 IgG 0.108 1.114 0.035 1.007, 1.231
Disease severity score 0.138 1.148 0.315 0.977, 1.501
Disease activity index -0.711 0.491 0.035 0.254, 0.950
  1. aA P-value >0.05 was not considered statistically significant. ACA, anti-centromere-associated protein antibodies; ANA, anti-nuclear antibodies; CRP, C-reactive protein; ESR, erythrocyte sedimentation rate; mRss, modified Rodnan skin score.