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Table 2 Test performance characteristics of SE, anti-CCP and RF for RA association

From: The phenotype and genotype of rheumatoid arthritis in the Democratic Republic of Congo

Parameter

Patients

% (n)

Controls

% (n)

PPV

NPV

Specificity

sensitivity

OR

95% CI

P-value

SE

positive

35.1 (13)

12.5 (3)

81

47

87

35

3.8

0.9 to 15.1

0.07

 

negative

64.9 (24)

87.5 (21)

       

RF

positive

34.7 (25)

3.0 (2)

93

58

97

35

17.3

3.9 to 76.6

<0.0001

 

negative

65.2 (47)

97.0 (65)

       

anti-CCP

positive

47.2 (34)

3.0 (2)

94

63

97

47

29.1

6.6 to 127.9

<0.0001

 

negative

52.7 (38)

97.0 (65)

       
  1. Anti-CCP, anti-cyclic citrullinated peptide; NPV, negative predictive value; PPV, positive predictive value; RA, rheumatoid arthritis; RF, rheumatoid factor; SE, shared epitope