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Table 2 Test performance characteristics of SE, anti-CCP and RF for RA association

From: The phenotype and genotype of rheumatoid arthritis in the Democratic Republic of Congo

Parameter Patients
% (n)
Controls
% (n)
PPV NPV Specificity sensitivity OR 95% CI P-value
SE positive 35.1 (13) 12.5 (3) 81 47 87 35 3.8 0.9 to 15.1 0.07
  negative 64.9 (24) 87.5 (21)        
RF positive 34.7 (25) 3.0 (2) 93 58 97 35 17.3 3.9 to 76.6 <0.0001
  negative 65.2 (47) 97.0 (65)        
anti-CCP positive 47.2 (34) 3.0 (2) 94 63 97 47 29.1 6.6 to 127.9 <0.0001
  negative 52.7 (38) 97.0 (65)        
  1. Anti-CCP, anti-cyclic citrullinated peptide; NPV, negative predictive value; PPV, positive predictive value; RA, rheumatoid arthritis; RF, rheumatoid factor; SE, shared epitope