Table 1 Clinical findings at study entry in patients with early rheumatoid arthritis^a

Demographics

   Age, years (range)

52 (30 to 80)

   Sex, females/males

36/14

Smoking history, n (%)

   Current

8 (16)

   Former

9 (18)

   Never

33 (66)

   Disease duration, months

4 (1 to 12)

Autoantibodies

   Rheumatoid factor (RF), no. positive (%)

30 (60)

   Anti-CCP

39 (78)

   RF or anti-CCP

42 (84)

Inflammatory indices

   Erythrocyte sedimentation rate (ESR), mm/h (range)

23 (3 to 98)

   C-reactive protein (CRP), mg/L (range)

7.6 (0.2 to 118)

Disease activity

   DAS28-ESR

4.7 (1.6 to 8.1)

   Tender joint count (TJC), n (range)

8 (0 to 26)

   Swollen joint count (SJC), n (range)

3 (0 to 23)

   Clinical Disease Activity Index (CDAI)

19.2 (2 to 57.7)

   Health Assessment Questionnaire (HAQ)

0.35 (0 to 2.55)

Medications prior to study entry, n (%)

   Prednisone

13 (26)

   Nonsteroidal anti-inflammatory drug (NSAID)

30 (60)

   Methotrexate (MTX)

0

   Tumor necrosis factor (TNF) inhibitor

0