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Table 2 Distribution of total BML volume change when stratified by tertiles based on total baseline BML volume

From: Evaluation of bone marrow lesion volume as a knee osteoarthritis biomarker - longitudinal relationships with pain and structural changes: data from the Osteoarthritis Initiative

   Total BML volume change (by quartile with middle two quartiles collapsed)
Total baseline BML volume Total BML volume change
Median (min, max)
cm 3
'BML regression'
(Range: -12.7 to -0.8 cm 3 )
n (% of baseline tertile)
'Minimal or
no BML change'
(Range: -0.8 to 0.4 cm 3 )
n (% of baseline tertile)
'BML progression'
(Range: 0.4 to 10.2 cm 3 )
n (% of baseline tertile)
'No or Small BML volume'
(Range: 0.1 to 1.0 cm3)
0.0 (-0.7, 4.2) 0 (0.0%) 108 (80.6%) 26 (19.4%)
'Moderate BML volume'
(Range: 1.0 to 2.7 cm3)
-0.1 (-2.5, 5.0) 24 (17.8%) 68 (50.4%) 43 (31.9%)
'Large BML volume'
(Range: 2.7 to 15.5 cm3)
-1.1 (-12.7, 10.2) 77 (57.0%) 26 (19.3%) 32 (23.7%)
  1. The division of total baseline bone marrow lesion (BML) volume and total BML volume change was based on tertiles. n = 404.