Figure 4

Effects of PDGF, IGF and cartilage supernatant on CPC migration. The number of migrated cells without stimulation and stimulated with platelet-derived growth factor (PDGF) (10 ng/ml), IGF (100 ng/ml) or supernatant of unimpacted cartilage (supernatant (SN) ∅ trauma) and impacted cartilage (SN trauma), respectively, are depicted. The values represent the mean ± SEM with n ≥3. Statistical significance was evaluated by ANOVA followed by a Bonferroni multiple comparison post-test with *P < 0.05, **P < 0.01 and ***P < 0.001.