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Figure 2 | Arthritis Research & Therapy

Figure 2

From: A phase Ib multiple ascending dose study evaluating safety, pharmacokinetics, and early clinical response of brodalumab, a human anti-IL-17R antibody, in methotrexate-resistant rheumatoid arthritis

Figure 2

Relationship between interleukin 17 receptor occupancy levels and serum brodalumab concentrations. Each symbol represents an individual sample collected during the study for all patients receiving brodalumab. Circles indicate samples with detectable pharmacokinetic (PK) levels of serum brodalumab, and triangles indicate samples below the level of quantitation (LOQ).

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Arthritis Research & Therapy

ISSN: 1478-6362

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