Skip to main content

Advertisement

Table 6 Haematological and biochemical laboratory findings a

From: Remarkable prevalence of coeliac disease in patients with irritable bowel syndrome plus fibromyalgia in comparison with those with isolated irritable bowel syndrome: a case-finding study

Laboratory panels IBS IBS/FMS P value IBS/FMS cases classified by Marsh stage P value
(N = 125) (N = 104) (IBS vs. FMS) Marsh stage 0 (N = 39) Marsh stage 1 (N = 58) Marsh stage 3 (N = 7) (Marsh stages 1 and 3 vs. Marsh stage 0)
Haemoglobin, g/dl 13 ( 1) 13 (1) 1.000 13 (1) 14 (1) 13 (1) 0.271
WBC count, n × 103 7.6 (1) 7.0 (2) 0.002 7.6 (1) 6.7 (2) 5.8 (2) 0.002
Platelet count, n × 103 272 (37) 257 (54) 0.021 274 (37) 248 (60) 232 (57) 0.010
Prothrombin activity (%) 98 (5) 98 (9) 0.777 98.2 (8) 98 (10) 98 (4) 0.741
aPTT, seconds 34 (2) 35 (2) 0.024 35 (2) 33 (2) 33 (1) 0.019
Fibrinogen, mg/dl 261 (111) 349 (152) <0.001 259 (113) 385 (128) 552 (218) <0.001
Glucose, mg/dl 108 (27) 101 (20) 0.018 109 (27) 96 (13) 99 (9) 0.020
Urea, mg/dl 44 (23) 40 (14) 0.022 43 (21) 38 (7) 38 (8) 0.017
CK, IU/L 59 (7) 60 (9) 0.985 58 (7) 61 (10) 62 (12) 0.276
CRP, mg/L 0.6 (0.6) 0.5 (0.6) 0.211 0.6 (0.7) 0.5 (0.7) 0.3 (0.2) 0.466
IgG, g/L 9.7 (0.5) 9.9 (1.0) 0.098 9.6 (0.5) 10.2 (1.2) 9.6 (1.0) 0.107
IgA, g/L 2.4 (0.5) 2.6 (0.6) 0.126 2.4 (0.6) 2.7 (0.6) 2.4 (0.5) 0.008
IgM, g/L 1.8 (0.4) 1.9 (0.5 ) 0.126 1.9 (0.3) 1.9 (0.6) 1.6 (0.5) 0.722
Iron, μg/ml 68 (19) 80 (29) 0.001 66 (20) 89 (32) 91 (21) <0.001
Ferritin, ng/ml 56 (23) 88 (164) 0.821 48 (28) 114 (214) 90 (70) 0.064
TSI, μg/dl 20 (11) 24 (9) 0.001 20 (11) 25 (8) 25 (6) 0.001
Cholesterol, g/dl 176 (24) 174 (39) 0.293 192 (18) 166 (42) 144 (52) 0.001
AST, IU/L 20 (9) 23 (9) <0.001 21 (5) 25 (11) 30 (20) 0.269
ALT, IU/L 21 (6) 25 (13) 0.803 21 (7) 27 (17) 19 (10) 0.765
GGT, IU/L 23 (20) 28 (23) 0.074 24 (20) 31 (22) 23 (33) 0.060
ALP, IU/L 70 (23) 76 (26) 0.012 74 (30) 78 (23) 77 (22) 0.066
Bilirubin, mg/dl 0.7 (0.2) 0.8 (0.2) 0.639 0.7 (0.1) 0.7 (0.2) 0.9 (0.24) 0.591
TSH, μU/ml 1.8 (0.6) 3.1 (5.9) 0.209 1.9 (0.7) 4.1 (7.8) 1.2 (0.8) 0.157
Folate, ng/dl 10 (4) 9 (3) 0.019 10 (3) 8 (3) 10 (5) 0.019
Vitamin B12, pg/ml 451 (168) 521 (206) 0.002 450 (170) 555 (213) 636 (238) 0.001
RF, IU/ml 13 (1) 13 (2) 0.858 13 (1) 13 (2) 14 (2) 0.775
ANAs (+) 4 (3) 29 (28) <0.001 3 (8) 23 (40) 3 (43) 0.002
Titres        
1:160 4 (3) 23 (22) <0.001 4 (10) 18 (31) 1 (14) 0.004
1:320 3 (3) NA 2 (3) 1 (14) NA
1:640 3 (3) NA 2 (3) 1 (14) NA
Staining pattern        
Speckled 4 (3) 25 (24) <0.001 4 (10) 21 (34) NA
Homogeneous 2 (2) NA 1 (2) 1 (14) NA
Nucleolar 2 (2) NA 2 (29) NA
Anti-TPO (+) 12 (11) NA 10 (17) 2 (29) 0.011
Serum levels, IU/ml 31 (108) NA 51 (140) 40 (72) NA
AMAs (+) 5 (4) NA 4 (7) 1 (0) NA
Titres        
1:160 1 (1) NA 1 (2) NA
1:320 2 (2) NA 1 (3) 1 (14) NA
1:640 2 (2) NA 2 (3) NA
  1. aALP, alkaline phosphatase; ALT, alanine aminotransferase; AMA, antimitochondrial antibody; ANA, antinuclear antibody; Anti-TPO, antithyroid peroxidase antibody; aPTT, activated partial thromboplastin time; AST, aspartate aminotransferase; CK, creatine kinase; CRP, C-reactive protein; GGT, γ-glutamyl transpeptidase; Ig, immunoglobulin; NA, not applicable; RF, rheumatoid factor; TSH, thyroid-stimulating hormone; TSI, Transferrin Saturation Index; WBC, white blood cell. Values are expressed as mean and standard deviation or total value and percentage.