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Table 3 Drug classes that failed to show superiority over placebo in reducing fibromyalgia syndrome symptoms

From: Review of pharmacological therapies in fibromyalgia syndrome

class (drug)

Number of studies /participants/duration of trial in weeks

Antiviral agents (valacyclovir)

1/30/6

Anxiolytics

 

Alprazolam

1/31/8

Bromazepam

1/84/8

Dopamine agonists

 

  • Pramiprexole

1/60/12a

  • Ropirinol

1/181/12

  • Terguride

1/99/12

Hormones

 

Calcitonin

1/11/4

Dehydroepiandrosteron

1/52/4

Prednisone

1/20/2

Hypnotics

 

Zolpidem

1/14/8

Interferon

1/28/4

Ketamine (intravenous)

1/20/0,5

Local anesthetics (intravenous): Lidocaine

3/177/4

Neuroleptics: Ritanserin

1/24/16

Serotonin receptor antagonists

 

Tropisetron

2/261/1

Odansetron

1/42/1

  1. A pooled analysis was conducted in case of more than one study [16]. aPramiprexole was superior to placebo [33].
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Arthritis Research & Therapy

ISSN: 1478-6362

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