The association between ANKH promoter polymorphism and chondrocalcinosis is independent of age and osteoarthritis: results of a case–control study

Table 4 Association between chondrocalcinosis and single-nucleotide polymorphisms in the combined dataset

	Common allele	Rare allele	MAF, %		OR_GENOTYPE(95% CI)	P	aOR_GENOTYPE(95% CI)	P
	Common allele	Rare allele	CC+	CC-	OR_GENOTYPE(95% CI)	P	aOR_GENOTYPE(95% CI)	P
-4bpG > A 5′ UTR	G:G	A:A	10.6	8.1	1.36 (1.12-1.65)	0.002	1.39 (1.14-1.69)	0.001
rs3045	T:T	C:C	12.4	9.9	1.29 (1.08-1.55)	0.006	1.31 (1.09-1.58)	0.005
rs39968	C:C	T:T	28.8	30.8	0.91 (0.80-1.04)	0.155	0.91 (0.80-1.04)	0.156
rs875525	C:C	T:T	28.1	25.0	1.18 (1.03-1.34)	0.014	1.18 (1.03-1.35)	0.015
rs1800562	G:G	A:A	8.3	7.6	1.10 (0.89-1.36)	0.386	1.13 (0.91-1.40)	0.273
rs1799945	C:C	G:G	16.9	14.6	1.19 (1.02-1.39)	0.032	1.18 (1.00-1.38)	0.047

5′ UTR, 5′ untranslated region; aOR_GENOTYPE, adjusted genotype odds ratio; CC, chondrocalcinosis; CI, confidence interval; MAF, minor allele frequency; OR_GENOTYPE, genotype odds ratio.

ISSN: 1478-6362