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Table 4 Association between chondrocalcinosis and single-nucleotide polymorphisms in the combined dataset

From: The association between ANKH promoter polymorphism and chondrocalcinosis is independent of age and osteoarthritis: results of a case–control study

  Common allele Rare allele MAF, % ORGENOTYPE(95% CI) P aORGENOTYPE(95% CI) P
CC+ CC-
-4bpG > A 5′ UTR G:G A:A 10.6 8.1 1.36 (1.12-1.65) 0.002 1.39 (1.14-1.69) 0.001
rs3045 T:T C:C 12.4 9.9 1.29 (1.08-1.55) 0.006 1.31 (1.09-1.58) 0.005
rs39968 C:C T:T 28.8 30.8 0.91 (0.80-1.04) 0.155 0.91 (0.80-1.04) 0.156
rs875525 C:C T:T 28.1 25.0 1.18 (1.03-1.34) 0.014 1.18 (1.03-1.35) 0.015
rs1800562 G:G A:A 8.3 7.6 1.10 (0.89-1.36) 0.386 1.13 (0.91-1.40) 0.273
rs1799945 C:C G:G 16.9 14.6 1.19 (1.02-1.39) 0.032 1.18 (1.00-1.38) 0.047
  1. 5′ UTR, 5′ untranslated region; aORGENOTYPE, adjusted genotype odds ratio; CC, chondrocalcinosis; CI, confidence interval; MAF, minor allele frequency; ORGENOTYPE, genotype odds ratio.