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Figure 4 | Arthritis Research & Therapy

Figure 4

From: Generation of disease-specific induced pluripotent stem cells from patients with rheumatoid arthritis and osteoarthritis

Figure 4

In vitro osteogenic differentiation of rheumatoid arthritis and osteoarthritis induced pluripotent stem cells. To induce osteogenic differentiation, rheumatoid arthritis (RA) and osteoarthritis (OA) induced pluripotent stem cells (iPSCs) were cultured in E8 medium or osteogenic differentiation medium (ODM) for 7 days. Osteogenic differentiation was determined by the fluorescence detection for mineralization. Osteogenic mineralization was detected in both ODM-treated RA iPSCs (A) and OA iPSCs (B) by fluorescence microscope (fluorescein isothiocyanate (FITC)).

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Arthritis Research & Therapy

ISSN: 1478-6362

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