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Table 8 Explorative analysis of potential predictors of cardiovascular events during follow-up in systemic sclerosis and systemic lupus erythematosus patients a

From: Atherosclerotic plaques occur in absence of intima-media thickening in both systemic sclerosis and systemic lupus erythematosus: a duplexsonography study of carotid and femoral arteries and follow-up for cardiovascular events

  SSc and SLE (n = 129)
Variable Beta coefficient Unadjusted hazard ratio (95% CI) P value
SSc versus SLE -0.173 0.84 (0.33 to 2.10) 0.712
Age (per 5 years) 0.262 1.30 (1.10 to 1.54) 0.003
Male sex 2.833 17.00 (5.99 to 48.22) <0.001
Carotid and femoral artery plaque    
 Group 3 (CP and FP) versus group 1 (no plaque) 2.595 13.40 (2.99 to 59.95) <0.001
 Group 3 (CP and FP) versus group 2 (CP or FP) 2.672 14.47 (2.51 to 83.55) 0.003
 Group 2 (CP or FP) versus group 1 (no plaque) -0.077 0.93 (0.12 to 7.39) 0.942
Arterial hypertension 1.678 5.35 (1.91 to 15.02) <0.001
Nicotine use (per 5 pack-years) 0.143 1.15 (1.04 to 1.28) 0.005
Coronary heart disease 2.592 13.36 (4.67 to 38.20) <0.001
Age at diagnosis (per 5 years) 0.075 1.20 (1.04 to 1.39) 0.014
C-reactive protein (per mg/dl) 0.220 1.25 (0.98 to 1.59) 0.079
  1. CI, confidence interval; CP, carotid artery plaque; FP, femoral artery plaque; SLE, systemic lupus erythematosus; SSc, systemic sclerosis.
  2. aOnly variables suggested for multivariate Cox regression analysis are reported; complete report available in Additional file 3.